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Development Times and Approval Success Rates for Drugs to Treat Infectious Diseases

September 10, 2019

Joseph A. DiMasi, Ph.D., Maria I. Florez, MS, Stella Stergiopoulos, MS-MPH, Yaritza Peña, Zachary Smith, MA, Michael Wilkinson MPH, Kenneth A. Getz, MBATufts Center for the Study of Drug Development. Clin Pharmacol Ther. 2019 Sep 10.

Integrated Bioinformatic Analyses and Immune Characterization of New Neisseria gonorrhoeae Vaccine Antigens Expressed during Natural Mucosal Infection

September 20, 2019

Zhu, T., R. McClure, O.B. Harrison, C.A. Genco, P. Massari. Vaccines (Basel). 2019 Oct 17;7(4):153.

Vibrio cholerae residing in food vacuoles expelled by protozoa are more infectious in vivo

September 30, 2019

Espinoza-Vergara G, Noorian P, Silva-Valenzuela CA, Raymond BBA, Allen C, Hoque MM, Sun S, Johnson MS, Pernice M, Kjelleberg S, Djordjevic SP, Labbate M, Camilli A, McDougald D. Nat Microbiol. 2019 Dec;4(12):2466-2474.

Adjunctive Host-Directed Therapy with Statins Improves Tuberculosis-Related Outcomes in Mice

October 12, 2019

Noton K Dutta, Natalie Bruiners, Matthew D Zimmerman, Shumin Tan, Véronique Dartois,Maria L Gennaro, Petros C Karakousis. J Infect Dis. 2019 Oct 12. pii: jiz517.

Integrase Strand Transfer Inhibitor (INSTI)-Resistance Mutations for the Surveillance of Transmitted HIV-1 Drug Resistance

October 16, 2019

J Antimicrob Chemother. 2019 Oct 16. pii: dkz417. [Epub ahead of print].

Transcriptome Signatures Predict Drug Synergy and Clinical Regimen Efficacy Against Tuberculosis

November 12, 2019

Ma S, Jaipall S, Larkins-Ford J, Lohmiller J, Aldridge BB, Sherman D, Chandrasekaran. MBio. 2019 Nov 12;10(6). e02627-19.

Automatic Detection of Granuloma Necrosis in Pulmonary Tuberculosis Using a Two-Phase Algorithm

December 7, 2019

Kus P, Gurcan MN, Beamer G. Microorganisms. 2019, 7(12), 661.

Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model

December 10, 2019

Kjellin, J., Pränting, M., Bach, F., Vaid, R., Edelbroek, B., Li, Z., Hoeppner, M.P., Grabherr, M., Isberg, R.R., Hagedorn, M., Soderbom, F. BMC Genomics. 2019 Dec 10;20(1):961.

Sporulation and Germination in Clostridial Pathogens

December 19, 2019

Aimee Shen, Adrianne N. Edwards2, Mahfuzur R. Sarker, Daniel Paredes-Sabja. Microbiol Spectr. 2019 Nov;7(6):10.1128/microbiolspec.GPP3-0017-2018.

HIV-Related Peer Support in Dar es Salaam: a Pilot Questionnaire Inquiry

December 26, 2019

Kiekens A, Dehens J, de Hemptinne M, Galouchka M, Sajud A, Vanhoorebeeck C, van Otzel RP, Wyszkowsk M, Baert S, Bernard EJ, Nova Blanco JR, Dierck T, Mosha F, Sanged RZ, Theys K, Van den Eede A, R Jordan MR, Vandamme A-M. Transdisciplinary Insights. Volume 3, Number 1, 26 December. 2019.