LCDRD

Levy CIMAR's Laboratory for Combinatorial Drug Regimen Design (LCDRD)

Advanced Facilities for Cutting-Edge Research Offering Fee-for-Service Contracts.

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Featured Trainees

Levy CIMAR's Featured Trainees

Here we highlight trainees (students and professionals) who stand out for their efforts in the fight against antimicrobial resistance.

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Education

Reaching Out to Brockton High

33 Sophomores and Seniors presented their original experiments and data on AMR to a wide audience at Tufts University and Tufts Medical Center.

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CIMAR

Levy CIMAR

Innovating to Protect Humanity from the Global Threat of Antimicrobial Resistance: Integrating Solutions Across Human and Veterinary Medicine, Stewardship, and Awareness.

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Research

Multidrug Therapies

Using Combination Chemotherapies to Cure Otherwise Untreatable Infections.

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Our Mission

Innovating to Protect Humanity from the Global Threat of Antimicrobial Resistance: Integrating Solutions Across Human and Veterinary Medicine, Stewardship, and Awareness

—  Latest Updates

News

CIMAR Outreach Day Provides High Schoolers Rare Educational and Networking Opportunities

The Tufts Center for Integrated Management of Antimicrobial Resistance hosted 33 students from Boston-area Brockton High School last week for a science outreach event. The students presented posters depicting original experiments and data on antimicrobial resistance to a wide audience of Tufts University and Tufts Medical Center graduate students, postdoctoral fellows, faculty, and clinicians.

Tufts Researchers Find Link Between Dog-Human Antibiotic Resistance

For many people, pets are family; just as close to them as the humans in their life. However, a new study suggests that closeness can create a concerning health issue making prescribed medicines less effective. …

IDSA announces Tufts Medical Center Among Recipients of Antimicrobial Stewardship Centers of Excellence Designation

The Infectious Diseases Society of America (IDSA) announced today the recipients of its Antimicrobial Stewardship Centers of Excellence (CoE) designation. …

Events

Drug-Resistant Superbugs: CIMAR Symposium Examines the Intersection of People, Animals, Food, and the Environment, and Their Impact on Health

April 9, 2019

The Tufts Center for Integrated Management of Antimicrobial Resistance (CIMAR) held its first symposium in Boston on March 18th. The event brought together over 175 clinicians and researchers from academia, medicine, and industry, all interested in fighting drug-resistant diseases via a “One Health” approach. One Health prioritizes the relationship among people, animals, the environment, and the foods we all consume as critical avenues by which drug-resistant bacteria spread from one to another

Metabolic Modeling Predicts Unique Drug Targets in Lyme Disease Pathogen B. burgdorferi – TUSM’s Peter Gwynne, PhD

February 23, 2023

We were pleased to hear from Bryan Lenneman, Ph.D., today on “Engineering Phages as Novel Antimicrobials Targeting Gram-Negative Pathogens.” Dr. Lenneman is a Research Fellow at Massachusetts General Hospital whose research interests include utilizing synthetic biology to develop novel therapeutics against diseases associated with dysbiosis of the human gut microbial community.

Superbugs From Their Backyards and Beyond: Brockton High Schoolers Present “Tiny Earth” Findings to Levy CIMAR; Tufts Community

January 13, 2026

CIMAR hosted 33 students from Boston-area Brockton High School last week for a rare educational and networking opportunity. Students presented posters depicting original experiments and data on antimicrobial resistance to a wide audience of Tufts University and Tufts Medical Center members.

Our Trainees

Ashley Luo

Ashley Luo

Ashley Luo, Second-Year Molecular Microbiology (MERGE-ID Track) PhD Candidate

Maryam Utegulova

Maryam Utegulova

Maryam Utegulova, 2025 Recipient of the Levy CIMAR Undergraduate Summer Internship in Science and Medicine

Mallika Subramanian

Mallika Subramanian

Mallika Subramanian, 2025 Recipient of the Levy CIMAR Undergraduate Summer Internship in Science and Medicine

Publications

A New Era for Global Environmental Surveillance of Infectious Disease

Amy Pickering

Environ Sci Technol. 2026 Apr 30. doi:

Restoration of daptomycin sensitivity with adjunctive cefazolin is associated with C-terminal MprF mutations in MRSA bacteremia isolates

Kathleen P Davis, Husain Poonawala, Connor Murphy, Cheleste Thorpe, Adriana Rosato, Bree B Aldridge

Antimicrob Agents Chemother. 2026 Apr 27:e0154725.

An RNA-to-RNA Pipeline for Rapid Antiviral Antibody Development

Edgar A Hodge, Jacob Archer, Jacqueline S Anderson, Nikole L Warner, Jacque Tremblay, Thomas Klose, Stephanie Park, Troy Hinkley, Amit P Khandhar, Richard Kuhn, Charles Shoemaker, Jesse H Erasmus

Mol. Ther. 2026 Apr 9:S1525-0016(26)00280-7.

Antibiotic dose-response curves can measure antibiotic activity against Mycobacterium abscessus and Mycobacterium peregrinum

Husain Poonawala, Kathleen Davis, Myles E. Kenny, Ares Alivisatos, Nhi Van, Tracy Washington, Vinicius Calado Nogueira de Moura, Charles L. Daley, Bree B. Aldridge

Antimicrob Agents Chemother. 2026 Apr 6:e0187625.

Differential targeting of human pyroptotic caspase-5 and caspase-4 by Shigella OspC2 and OspC3

Kyungsub Kim #, Marcos Antonio Valdespino Diaz #, Rowan M Karr, Michele E Muscolo, Lisa Goers, Truelian Yu, Tera C Levin, Jonathan N Pruneda, Cammie F Lesser

mBio. 2026 Mar 11;17(3):e0385525.

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Our Values

The Levy CIMAR is committed to a culture of diversity, equity, and inclusion both within our organization and for all people who are impacted by our work. We strive for health equity for people from all backgrounds and identities, and we actively support societal and institutional structures that promote justice and equality. We are also committed to being a safe, respectful, and inclusive environment for our trainees, staff, faculty, affiliates, and partners. One Health acknowledges the interconnectedness of allhumans, along with animals and our environments. Antimicrobial resistance impacts us all.