Evaluating the relationship between community water and sanitation access and the global burden of antibiotic resistance: an ecological study
June 30, 2023
Erica R Fuhrmeister, Abigail P Harvey, Maya L Nadimpalli, Karin Gallandat, Argaw Ambelu, Benjamin F Arnold, Joe Brown, Oliver Cumming, Ashlee M Earl, Gagandeep Kang, Samuel Kariuki, Karen Levy, Chris E Pinto Jimenez, Jenna M Swarthout, Gabriel Trueba, Pablo Tsukayama, Colin J Worby, Amy J Pickering
Establishing a baseline of antibiotic use in Massachusetts jails reveals heterogeneity in quantity of prescriptions and duration of therapy
June 21, 2023
Bart R Szewczyk, Rebecca Tenner, Emily Grussing, Maureen Campion, Gabriela Andujar Vazquez, Tara Bylsma, Shira Doron, Alysse G Wurcel
Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus
June 6, 2023
Nhi Van, Yonatan N. Degefu, Pathricia A. Leus, Jonah Larkins-Ford, Jacob Klickstein, Florian P. Maurer, David Stone, Husain Poonawala, Cheleste M. Thorpe, Trever C. Smith II, Bree B. Aldridge
Are fermented foods an overlooked reservoir of antimicrobial resistance?
June 5, 2023
Benjamin E. Wolfe
Despite their many cultural, culinary, and health benefits, fermented foods may amplify and disseminate antimicrobial resistance in our food supply. This review summarizes our current understanding of the diversity, distribution, and potential risks of antimicrobial resistance in fermented foods and beverages. Most studies have focused on antibiotic resistance genes (ARGs) in lactic acid bacteria and coagulase-negative Staphylococcus species. Resistance to tetracyclines, penicillins, chloramphenicol, and macrolides is frequently reported. Several studies have demonstrated that ARGs have the potential to be transferred from fermentation microbes to pathogens. Most research has used culture-based or metagenomic surveys or ARGs at the point of production, and few studies have traced the fate of ARGs when ferments are consumed. Cases of humans being directly harmed by resistant microbes in ferments have not been reported, but these foods provide a farm-to-gut pipeline for current and future antimicrobial resistance in our food supply.
Bacteriophages potentiate the effect of antibiotics by eradication of persister cells and killing of biofilm-forming cells
May 29, 2023
Javiera Vera-Mansilla, Cecilia A Silva-Valenzuela, Patricio Sánchez, Roberto C Molina-Quiroz
Penicillium molds impact the transcriptome and evolution of the cheese bacterium Staphylococcus equorum
May 23, 2023
Ruby Ye, Christopher Tomo, Neal Chan, Benjamin E Wolfe
Exploration of a Potential DOOR Endpoint for Complicated Intra-Abdominal Infections Using Nine Registrational Trials for Antibacterial Drugs
April 19, 2023
Tori Kinamon, Ramya Gopinath, Ursula Waack, Mark Needles, Daniel Rubin, Deborah Collyar, Sarah B Doernberg, Scott Evans, Toshimitsu Hamasaki, Thomas L Holland, Jessica Howard-Anderson, Henry Chambers, Vance G Fowler, Jr, Sumati Nambiar, Peter Kim, Helen W Boucher
Which trial do we need? Long-acting glycopeptides versus oral antibiotics for infective endocarditis in patients with substance use disorder
April 9, 2023
Alysse G. Wurcel, Daniel C. DeSimone, Laura Marks, Larry M. Baddour, Parham Sendi
One Health WASH: an AMR-smart integrative approach to preventing and controlling infection in farming communities
March 7, 2023
Chris E Pinto Jimenez, Sarai M Keestra, Pranav Tandon, Amy J Pickering, Arshnee Moodley, Oliver Cumming , Clare I R Chandler
Demonstrating the importance of local culture and susceptibility data: antibiograms from dogs at a veterinary tertiary care center
March 1, 2023
Kendall Leet-Otley, Claire L Fellman, Annie S Wayne, Kirthana Beaulac, Ian M DeStefano, Kelly Chambers, Kady B Marino, Shira Doron
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- An RNA-to-RNA Pipeline for Rapid Antiviral Antibody DevelopmentApril 9, 2026
- Antibiotic dose-response curves can measure antibiotic activity against Mycobacterium abscessus and Mycobacterium peregrinumApril 6, 2026