CATEGORY

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The piglet acute diarrhea model for evaluating efficacy of treatment and control of cryptosporidiosis

August 27, 2018

Cryptosporidium spp. are ranked as the second leading pathogens causing life-threatening diarrhea in children under 2 years of age.

Antimicrobial susceptibility and ribotypes of Clostridium difficile isolates from a Phase 2 clinical trial of ridinilazole (SMT19969) and vancomycin.

Aug, 2018

Enhanced preservation of the human intestinal microbiota by ridinilazole, a novel Clostridium difficile-targeting antibacterial, compared to vancomycin.

Aug, 2018

Cheleste M. Thorpe , Anne V. Kane, Justin Chang, Albert Tai, Richard J. Vickers, and David R. Snydman

Stereospecific Synthesis of the Saccharosamine-Rhamnose-Fucose Fragment Present in Saccharomicin B

July 17, 2018

Marissa Bylsma and Clay S. Bennett

Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action

July, 2018

Maikel Boot, Susanna Commandeur, Amit K. Subudhi, Meriem Bahira, Trever C. Smith, II, Abdallah M. Abdallah, Mae van Gemert, Joël Lelièvre, Lluís Ballell, Bree B. Aldridge, Arnab Pain, Alexander Speer, Wilbert Bitter

Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis

June 26, 2018

Sangun Lee, Melanie Ginese, Gillian Beamer, Hillary R. Danz, Donald J. Girouard, Susan P. Chapman-Bonofiglio, Minhee Lee, Matthew A. Hulverson, Ryan Choi, Grant R. Whitman, Kayode K. Ojo, Samuel L. M. Arnold, Wesley C. Van Voorhis, Saul Tzipori

A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii

May 24, 2018

Edward Geisinger, Nadav J. Mortman, Germán Vargas-Cuebas, Albert K. Tai

Reagent-Controlled Synthesis of the Branched Trisaccharide Fragment of the Antibiotic Saccharomicin B

May 23, 2018

Sameh E. Soliman and Clay S. Bennett

Fluorescent Mycobacterium Tuberculosis Reporters: Illuminating Host-Pathogen Interactions

April 1, 2018

The pathogenesis of Mycobacterium tuberculosis (Mtb) is intrinsically linked to its intimate and enduring interaction with its host, and understanding Mtb–host interactions at a molecular level is critical to attempts to decrease the significant burden of tuberculosis disease.

Evaluation of the In Vitro Activity of Eravacycline against a Broad Spectrum of Recent Clinical Anaerobic Isolates.

Apr, 2018

David R. Snydman, Laura A. McDermott, Nilda V. Jacobus, Kathryn Kerstein, Trudy H. Grossman, Joyce A. Sutcliffe