Fluorescent Mycobacterium Tuberculosis Reporters: Illuminating Host-Pathogen Interactions
April 1, 2018
The pathogenesis of Mycobacterium tuberculosis (Mtb) is intrinsically linked to its intimate and enduring interaction with its host, and understanding Mtb–host interactions at a molecular level is critical to attempts to decrease the significant burden of tuberculosis disease.
CASSIA: An assistant for identifying clinically and statistically significant decreases in antimicrobial susceptibility
April 9, 2018
M. L. Tlachac, Elke Rundensteiner, Kerri Barton, Scott Troppy, Kirthana Beaulac, Shira Doron, Jian Zou,
Reagent-Controlled Synthesis of the Branched Trisaccharide Fragment of the Antibiotic Saccharomicin B
May 23, 2018
Sameh E. Soliman and Clay S. Bennett
A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii
May 24, 2018
Edward Geisinger, Nadav J. Mortman, Germán Vargas-Cuebas, Albert K. Tai
Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis
June 26, 2018
Sangun Lee, Melanie Ginese, Gillian Beamer, Hillary R. Danz, Donald J. Girouard, Susan P. Chapman-Bonofiglio, Minhee Lee, Matthew A. Hulverson, Ryan Choi, Grant R. Whitman, Kayode K. Ojo, Samuel L. M. Arnold, Wesley C. Van Voorhis, Saul Tzipori
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action
July, 2018
Maikel Boot, Susanna Commandeur, Amit K. Subudhi, Meriem Bahira, Trever C. Smith, II, Abdallah M. Abdallah, Mae van Gemert, Joël Lelièvre, Lluís Ballell, Bree B. Aldridge, Arnab Pain, Alexander Speer, Wilbert Bitter
Stereospecific Synthesis of the Saccharosamine-Rhamnose-Fucose Fragment Present in Saccharomicin B
July 17, 2018
Marissa Bylsma and Clay S. Bennett
Enhanced preservation of the human intestinal microbiota by ridinilazole, a novel Clostridium difficile-targeting antibacterial, compared to vancomycin.
Aug, 2018
Cheleste M. Thorpe , Anne V. Kane, Justin Chang, Albert Tai, Richard J. Vickers, and David R. Snydman
Antimicrobial susceptibility and ribotypes of Clostridium difficile isolates from a Phase 2 clinical trial of ridinilazole (SMT19969) and vancomycin.
Aug, 2018
The piglet acute diarrhea model for evaluating efficacy of treatment and control of cryptosporidiosis
August 27, 2018
Cryptosporidium spp. are ranked as the second leading pathogens causing life-threatening diarrhea in children under 2 years of age.
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