Publications
2019
Publications
Definitions and Guidelines for Research on Antibiotic Persistence
Nature Reviews Microbiology – April 12. 2019.
2019
Publications
Artificial Intelligence and Patient-centric Approaches to Advance Pharmaceutical Innovation
Kenneth I. Kaitin, PhD, Tufts Center for the Study of Drug Development. Clin Ther. 2019 Aug; 41(8):1406-1407.
2019
Publications
The Effect of Respiratory Viral Assay Panel on Antibiotic Prescription Patterns at Discharge In Adults Admitted with Mild to Moderate Acute Exacerbation of COPD: A Retrospective Before- After Study
Tickoo M, Ruthazer R, Bardia A, Doron S, Andujar-Vazquez GM, Gardiner BJ, Snydman DR, Kurz SG. BMC Pulm Med. 2019 Jul 1;19(1):118.
2019
Publications
Discovery of Peptide Antibiotics Composed of d-Amino Acids
Emel Adaligil, Kalyani Patil, Marissa Rodenstein, Krishna Kumar. ACS Chem Biol. 2019 Jul 19;14(7):1498-1506.
2019
Publications
Amino Acid Biosynthetic Pathways Are Required for Klebsiella pneumoniae Growth in Immunocompromised Lungs and Are Druggable Targets during Infection
Rebecca J. Silver, Michelle K. Paczosa, Anne L. McCabe, Joan-Miquel Balada-Llasat, James D. Baleja, Joan Mecsas. Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e02674-18.
2019
Publications
U.S.-Based National Surveillance for Fidaxomicin Susceptibility of Clostridioides difficile-Associated Diarrheal Isolates from 2013 to 2016
C. M. Thorpe, L. A. McDermott, M. K. Tran, J. Chang, S. G. Jenkins, E. J. C. Goldstein, R. Patel, B. A. Forbes, S. Johnson, D. N. Gerding, D. R. Snydman. Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00391-19.
2019
Publications
Usage Patterns of Carbapenem Antimicrobials in Dogs and Cats at a Veterinary Tertiary Care Hospital
Alison Smith, Annie S. Wayne, Claire L. Fellman, Marieke H. Rosenbaum. J Vet Intern Med. 2019 Jul;33(4):1677-1685.
November 14, 2018
Publications
Synthesis of the Non-Reducing Hexasaccharide Fragment of Saccharomicin B
ACS Publications, Organic Letters, 2018 Nov 14. doi: 10.1021/acs.orglett.8b03333
November, 2018
Publications
An Experimental Pipeline for Initial Characterization of Bacterial Type III Secretion System Inhibitor Mode of Action Using Enteropathogenic Yersinia
Dozens of Gram negative pathogens use one or more type III secretion systems (T3SS) to disarm host defenses or occupy a beneficial niche during infection of a host organism.
October 31, 2018
Publications
The PARE Project: A Short Course-Based Research Project for National Surveillance of Antibiotic-Resistant Microbes in Environmental Samples
Course-based research experiences (CREs) have been proposed as an inclusive model to expose all students, including those at institutions without a strong research infrastructure, to research at an early stage.
October 12, 2018
Publications
Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection
Sarah B Doernberg, Thuy Tien Tram Tran, Steven Y C Tong, Mical Paul, Dafna Yahav, Joshua S Davis, Leonard Leibovici, Helen W Boucher, G Ralph Corey, Sara E Cosgrove, Henry F Chambers, Vance G Fowler, Scott R Evans, Thomas L Holland,
October, 2018
Publications
The landscape of intrinsic and evolved fluoroquinolone resistance in Acinetobacter baumannii includes suppression of drug-induced prophage replication
The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clinical efficacy of this antibiotic class. In Acinetobacter baumannii, the majority of clinical isolates now show high level resistance due to mutations in gyrA (DNA gyrase) and parC (Topo IV).