Publications
May 17, 2019
Publications
Sequential, Multiple-Assignment, Randomized Trials for COMparing Personalized Antibiotic StrategieS (SMART-COMPASS)
Evans, S. R., D. Follmann, Y. Liu, T. Holland, S.B. Doernberg, N. Rouphael, T. Hamasaki, Y. Jiang, J. J. Lok, T.T.T. Tran, A.D. Harris, V.G. Fowler Jr, H. Boucher, B.N. Kreiswirth, R.A. Bonomo, D. van Duin, D.L. Paterson, and H. Chambers. Clin Infect Dis. 2019 May 17;68(11):1961-1967.
February, 2019
Publications
Promises and Challenges of the Type Three Secretion System Injectisome as an Antivirulence Target
Antibiotic resistance is a major public health threat that has stimulated the scientific community to search for nontraditional therapeutic targets. Because virulence, but not the growth, of many Gram-negative bacterial pathogens depends on the multicomponent type three secretion system injectisome (T3SSi), the T3SSi has been an attractive target for identifying small molecules, peptides, and monoclonal antibodies that inhibit its function to render the pathogen avirulent.
February 11, 2019
Publications
Provincial and National Prevalence Estimates of Transmitted HIV-1 Drug Resistance in South Africa Measured Using Two WHO-Recommended Methods
Gillian M Hunt, Johanna Ledwaba, Monalisa Kalimashe, Anna Salimo, Siyabonga Cibane, Beverly Singh, Adrian Puren, Natalie Exner Dean, Lynn Morris, Michael R Jordan. Antivir Ther. 2019;24(3):203-21.
February 4, 2019
Publications
Potassium Response and Homeostasis in Mycobacterium Tuberculosis Modulates Environmental Adaptation and is Important for Host Colonization
Nathan J. MacGilvary, Yuzo L. Kevorkian, and Shumin Tan. PLoS Pathog. 2019 Feb 4;15(2):e1007591.
January 30, 2019
Publications
Prediction of ultra-high-order antibiotic combinations based on pairwise interactions
Itay Katzir, Murat Cokol, Bree B. Aldridge, and Uri Alon. PLoS Comput Biol 15(1): e1006774.
January, 2019
Publications
Parenterally Administered Vancomycin in 29 Dogs and 7 Cats (2003-2017)
Ian M. DeStefano Annie S. Wayne Elizabeth A. Rozanski Jonathan M. Babyak
Jan, 2019
Publications
Prophage induction, but not production of phage particles, is required for lethal disease in a microbiome-replete murine model of enterohemorrhagic E. coli infection.
Enterohemorrhagic Escherichia coli (EHEC) colonize intestinal epithelium by generating characteristic attaching and effacing (AE) lesions. They are lysogenized by prophage that encode Shiga toxin 2 (Stx2), which is responsible for severe clinical manifestations.
Jan, 2019
Publications
Partial Oral Therapy for Osteomyelitis and Endocarditis - Is It Time?
Antimicrobial resistance threatens health and global security, with an estimated 162,000 deaths per year in the United States caused by multidrug-resistant infections
2019
Publications
A Statewide Program to Improve Management of Suspected Urinary Tract Infection in Long-Term Care
Salem-Schatz S, Griswold P, Kandel R, Benjamin-Bothwell S, DeMaria A Jr, McElroy N, Bolstorff B, McHale E, Doron S. J Am Geriatr Soc. 2019 Nov 28. [Epub ahead of print].
2019
Publications
The Infectious Diseases Society of America's 10 × '20 Initiative (10 New Systemic Antibacterial Agents US Food and Drug Administration Approved by 2020): Is 20 × '20 a Possibility?
George H Talbot, Amanda Jezek, Barbara E Murray, Ronald N Jones, Richard H Ebright, Gerard J Nau, Keith A Rodvold, Jason G Newland, Helen W Boucher, Infectious Diseases Society of America. Clinical Infectious Diseases, ciz089.
2019
Publications
One for All, but Not All for One: Social Behavior During Bacterial Diseases
Kimberly M.Davis, Ralph R.Isberg. Trends in Microbiology, Cell Press. 2019 Jan;27(1):64-74.
2019
Publications
New age strategies to reconstruct tissue colonization and growth in cell culture systems
Fasciano, A.C., Mecsas, J. and Isberg, R.R. Microbiology Spectrum – March. 2019 vol. 7 no. 2.